Table of Contents
Mangosteen is a dark reddish-purple fruit of southeastern Asia with a thick skin and juicy flesh having a taste suggestive of both peach and pineapple.
Likewise: a tree (Garcinia mangostana) of the Saint-John’s- wort family that bears mangosteens. 
The progressive boost in awareness of the mangosteen outside of the Malay Island chain, its native variety, was a long and sluggish procedure. The few explorers who passed through the seas of Southeast Asia had more pressing issues to contend with than trying to transfer back to Europe and later the Americas an unique fruit that was so perishable and fragile. Even the seeds die in a week or two if permitted to dry out. There were much easier methods to make money. Spices, nuts, rare-earth elements, gems, plant and animal pharmaceuticals and hard goods were all more able to make the long ocean journey back with little reduction in quality. Nevertheless, live mangosteen plants were attempted before the 1800’s.
Most likely the best bibliography of the historic referrals to the mangosteen was assembled by Cora L. Feldkamp in 1946. This comprehensive collection included, in her words, “referrals on all aspects of the mangosteen- botany, culture, illness and bugs, ranges, composition, nutritive worth, culinary, hazardous effects, utilizes, economics, etc” Much of the website mangosteen.com relied on the extensive work done by Cora L. Feldkamp. It supplied a huge overview of the history of the mangosteen and its steady march towards contemporary times and greater familiarity in the Western Hemisphere and Europe.
The earlier transportation of plants outside of their native range required a good deal of planning and then luck when the mode of transportation was a boat on the ocean blues. Beyond the typical standard necessity of food and weaponry, live plant transport required more intricate measures i.e. Refitting the ship deck, lining the hull with copper to fend off seaborne wood parasites, developing special plant cases or building greenhouses on deck, storing additional fresh water, etc. A few of the earlier plant explorers did be successful very well in getting their accessions back to their home countries or colonies. Often the accessions changed ships in transit when a homeward-bound vessel helped a fellow countryman in getting their collected material back to the mother country. And often the collected product ended up being the residential or commercial property of a different country as a result of piracy. In this regard, the Spanish, French, Dutch, British, Portuguese and others all vied for control of various areas of the world and strove to produce monopolies in any and all commodities. The spice trade, furs, gums and waxes, natural dyes, ivory, silk, cotton and coffee consisted of much of the freight at sea in those times. A steady trend was emerging where the control of a product was more workable for a colonial power than outright control of the people of a nest or ownership and treaties for this purpose abounded. In the decades following their loss in the Revolutionary War, the British set to the task of checking out and strengthening their grip on particular trade routes on the seas. Plants were not just carried back to house countries from afar (3 ). Numerous colonizers also took plants and livestock the other method, ‘seeding’ the islands along the paths to attempt and guarantee a food supply in both instructions and a way of barter as well. Horses, pigs and goats existed as gifts to secure certain trade advantages and the result was a movement of germplasm of lots of species outside of their native ranges that would never be allowed today. The focus of this web site, the mangosteen, was just a bit player in this drama but played a role nonetheless.
The records that detail the motion of the mangosteen throughout the 18th and 19th century suggest that the first intro of the mangosteen in the UK returns to someone called Anton Pantaleon Hove. A. P. Hove (alternately Hoveau) was a Pole dispatched by Sir Joseph Banks to go and try to ‘acquire’ some better stress of cotton seeds from Gujarat, India. Apparently amongst his procurements were mangosteen plants that made it back to Plymouth, England in 1789 and which were then moved to Kew. Sir Joseph Banks, whose widespread appeal and renown resulting from his accompanying Captain Cook on his very first expedition, was then head of the Royal Botanical Gardens at Kew and president of the Royal Society. Banks was very actively included throughout this period in guiding, seeking advice from on and often personally funding tasks involving both plant and animal intros. Slowly however definitely, the effort was being made to present the mangosteen into the Western Hemisphere.
With regard to the history of the mangosteen, it ought to be noted that it was the other plant under consideration in an 18th century publication titled “A description of the mangostan and the bread-fruit” by John Ellis (mangostan was the word for the mangosteen in the Molucca Islands). The year was 1775 and John Ellis was utilizing his understanding of the tropics as a fellow of the Royal Society Of London to state upon the botanical treasures of away Africa and the Malay Island chain. The original intent of this work was to inform his Majesty “The Earl of Sandwich, First Lord of the Admiralty of Terrific BRITAIN” of a possibility that “seems conducive to the advantage of any part of the British Empire …”.
Ellis makes reference to Laurent Garcin, a French biologist who took a trip through the region in question collecting and describing the native plants in general and the mangosteen in particular. Linnaeus, a regular correspondent with Ellis, honored the work of Laurent Garcin by calling the genus Garcinia cambogia which includes the mangosteen after him. It is the radiant description of the mangosteen fruit by Garcin, Rumphius, and others that led Ellis to position it alongside the breadfruit as a prospect for retrieval and planting in the British colonies of the Caribbean. The publication of this paper was planned to motivate the financing of an expedition to the “East Indies” to restore these 2 plant species, the mangosteen and the breadfruit, to the West Indies for planting and growing. In this it prospered. The individual chosen for this journey based on the conclusions of this publication was none other than Captain Bligh. The British government in 1787 informed the West India Committee, a British plantation owners’ lobbying company in competition with the Royal Society of the Arts, that they would offer financing for this exploration. They acquired a ship commissioned as the “Bounty” for this function. As lots of know, Bligh required more than one attempt however did ultimately be successful in bringing back the bread fruit on the ship Providence. For this Bligh got the Gold Medal from the Royal Society of the Arts in 1793. Breadfruit then ended up being widely established throughout the Caribbean and Latin America. The very same success and notoriety could not be said for the other candidate in John Ellis’ work, the mangosteen, at that time.
The recommendations to the mangosteen stay rather sparse from completion of the 18th century to the mid-19th century. One event that stands out is that of the first recorded fruiting of the mangosteen in the UK in 1855. This feat was accomplished at Syon Park, the ancestral house of the Dukes of Northumberland, by their highly competent garden enthusiast John Ivison. The greenhouse complex was heated to preserve a stable tropical temperature level to offset the temperate British environment and this was managed in what were then known as stove houses. The seeds were obtained, so the post goes, by a Captain White from Calcutta in 1833. Based upon this and other short articles around that period, the timeframe would be that flowers formed on one or both of the two trees grown in big tubs in November of 1854. This would work out about right for fruit roughly 120 days or more later. It was specified that the tree with the flowers was about 15′ high and 9′ wide (a field grown tree in the tropics can produce at a much smaller sized size and in less years) but to pull this off in a greenhouse was quite an accomplishment. It was acknowledged as such by the Royal Horticultural Society at the time. The fruit got the Gold Banksian Medal, the very first time such an honor was attached to a single fruit. It is claimed by various web sites that Queen Victoria remained in participation when the fruit was presented but in point of fact there is no proof of that and the Queen more than likely was not. This would have been too relevant for the press to have ignored it in the posts of the time and none substantiate this claim. The Royal Archives just recently found a letter from Eleanor, the Duchess of Northumberland, dealt with to Queen Victoria describing that based on her (Eleanor’s) glowing description of the mangosteen to the Queen at a subsequent event, “… I now venture to ask to be permitted to send out to your Majesty, a Fruit of the Mangosteen, which has actually never been known to fruit out of its own nation; and this is therefore a things of really excellent interest and interest amongst Botanists.” Why would she offer to send one if the Queen had already been at any ceremony based on the fruit of the mangosteen? This letter is from Might 7, 1855 and there is no recorded proof at this time that the Queen ever received the fruit or tried it if it arrived. A good day to be a court taster! So it is possible that Queen Victoria tried a sample sent out over to her by Eleanor, Duchess of Northumberland, but there is no recorded proof of receipt at this time or tasting of the mangosteen by the Queen in 1855. None whatsoever. 
The mangosteen tree is really slow-growing, erect, with a pyramidal crown; obtains 20 to 82 feet (6-25 m) in height, has dark-brown or nearly black, flaking bark, the inner bark containing much yellow, gummy, bitter latex. The evergreen, opposite, short-stalked leaves are ovate-oblong or elliptic, leathery and thick, dark-green, a little shiny above, yellowish-green and dull below; 3 1/2 to 10 in (9-25 cm) long, 1 3/4 to 4 in (4.5-10 cm) broad, with obvious, pale midrib. New leaves are rosy. Flowers, 1 1/2 to 2 in (4-5 cm) broad and fleshy, might be male or hermaphrodite on the exact same tree. The former remain in clusters of 3-9 at the branch pointers; there are 4 sepals and 4 ovate, thick, fleshy petals, green with red areas on the outside, yellowish-red within, and lots of endurances though the aborted anthers bear no pollen. The hermaphrodite are borne singly or in pairs at the suggestions of young branchlets; their petals might be yellowish-green edged with red or mainly red, and are quickly shed.
The fruit, capped by the prominent calyx at the stem end and with 4 to 8 triangular, flat residues of the stigma in a rosette at the apex, is round, dark-purple to red-purple and smooth externally; 1 1/3 to 3 in (3.4-7.5 cm) in size. The rind is 1/4 to 3/8 in (6-10 mm) thick, red in cross-section, purplish-white on the inside. It includes bitter yellow latex and a purple, staining juice. There are 4 to 8 triangular segments of snow-white, juicy, soft flesh (really the arils of the seeds). The fruit might be seedless or have 1 to 5 totally established seeds, ovoid-oblong, rather flattened, 1 in (2.5 cm) long and 5/8 in (1.6 cm) large, that cling to the flesh. The flesh is a little acid and moderate to definitely acid in flavor and is well-known as remarkably luscious and tasty.
According to Corner, the fruit from seedling trees is fairly consistent; only one unique variation is understood which is in the Sulu Islands. The fruit is larger, the rind thicker than regular, and the flesh more acid; the flavor more pronounced. In North Borneo, an apparently wild type has only 4 carpels, each including a fully-developed seed, and this is probably not unique.
The mangosteen is ultra-tropical. It can not endure temperature levels listed below 40º F (4.44 º C), nor above 100º F (37.78 º C). Nursery seedlings are killed at 45º F (7.22 º C).
It is restricted in Malaya to elevations listed below 1,500 feet (450 m). In Madras it grows from 250 to 5,000 ft (76-1,500 m) above sea-level. Efforts to establish it north of 200 latitude have all stopped working.
It generally requires high climatic humidity and an annual rainfall of at least 50 in (127 cm), and no long periods of drought. In Dominica, mangosteens growing in an area having 80 in (200 cm) of rain annual required special care, however those in another area with 105 in (255 cm) and soil with better moisture- holding capacity, thrived.
The tree is not adjusted to limestone and does best in deep, rich natural soil, particularly sandy loam or laterite. In India, the most productive specimens are on clay containing much coarse product and a little silt. Sandy alluvial soils are unsuitable and sand low in humus adds to low yields. The tree requires great drainage and the water level should have to do with 6 feet (1.8 m) below ground level. However, in the Canal Zone, efficient mangosteen groves have actually been established where it is too damp for other fruit trees– in swamps needing drainage ditches in between rows and in scenarios where the roots were bathed with streaming water most of the year, in spite of the reality that standing water in nursery beds will eliminate seedlings. The mangosteen needs to be sheltered from strong winds and salt spray, in addition to saline soil or water.
Technically, the so-called “seeds” are not real seeds but adventitious embryos, or hypocotyl tubercles, inasmuch as there has actually been no sexual fertilization. When growth starts, a shoot emerges from one end of the seed and a root from the other end. But this root is short-term and is changed by roots which develop at the base of the shoot. The process of reproduction being vegetative, there is naturally little variation in the resulting trees and their fruits. A few of the seeds are polyembryonic, producing more than one shoot. The private nucellar embryos can be separated, if desired, before planting.
Inasmuch as the portion of germination is straight related to the weight of the seed, just plump, totally developed seeds should be picked for planting. Even these will lose viability in 5 days after elimination from the fruit, though they are viable for 3 to 5 weeks in the fruit. Seeds packed in lightly moistened peat moss, sphagnum moss or coconut fiber in airtight containers have actually remained feasible for 3 months. Just 22% germination has been realized in seeds crammed in ground charcoal for 15 days. Soaking in water for 24 hr expedites and improves the rate of germination. Typically, sprouting takes place in 20 to 22 days and is complete in 43 days.
Because of the long, fragile taproot and bad lateral root development, transplanting is notoriously tough. It needs to not be tried after the plants reach 2 feet (60 cm). At that time the depth of the taproot may exceed that height. There is higher seedling survival if seeds are planted straight in the nursery row than if very first grown in containers and then transplanted to the nursery. The nursery soil should be 3 feet (1 m) deep, at least. The young plants take 2 years or more to reach a height of 12 in (30 cm), when they can be taken up with a deep ball of earth and set out. Fruiting may take place in 7 to 9 years from planting but generally not for 10 or perhaps twenty years.
Traditional vegetative propagation of the mangosteen is tough. Numerous methods of implanting have actually stopped working. Cuttings and air-layers, with or without growth-promoting chemicals, normally fail to root or lead to warped, short-term plants. Inarching on various rootstocks has appeared promising at first but later incompatibility has actually been evident with all except G. Xanthochymus Hook. F. (G tinctoria Dunn.) Or G. Lateriflora Bl., now frequently utilized in the Philippines.
In Florida, approach-grafting has been successful just by planting a seed of G. Xanthochymus about 1 1/4 in (3 cm) from the base of a mangosteen seedling in a container and, when the stem of the G. Xanthochymus seedling has actually become 1/8 in (3 mm) thick, joining it onto the 3/16 to 1/4 in (5-6 mm) thick stem of the mangosteen at a point about 4 in (10 cm) above the soil. When the graft has actually recovered, the G. Xanthochymus seedling is beheaded. The mangosteen will make good progress having both root systems to grow on, while the G. Xanthochymus rootstock will establish extremely bit.
A spacing of 35 to 40 ft (10.7-12 m) is recommended. Planting is preferably done at the start of the rainy season. Pits 4 x 4 x 4 1/2 feet (1.2 x l. 2 x l. 3 m) are prepared at least one month beforehand, enriched with raw material and topsoil and delegated weather. The young tree is put in place very carefully so as not to hurt the root and given a heavy watering. Partial shading with palm leaves or by other methods must be preserved for 3 to 5 years. Indian growers give each tree routine feeding with well-rotted manure– 100 to 200 lbs (45-90 kg)– and peanut meal– 10 to 15 lbs (4.5-6.8 kg) overall, each year.
Some of the most fruitful mangosteen trees are growing on the banks of streams, lakes, ponds or canals where the roots are nearly constantly wet. However, dry weather just before flowering time and during blooming induces a good fruit-set. Where a moist planting website is not available, irrigation ditches need to be dug to make it possible to keep an appropriate supply of water and the trees are irrigated nearly daily throughout the dry season.
In Malaya and Ceylon, it is a typical practice to spread out a mulch of coconut husks or leaves to keep wetness. A 16-in (40-cm) mulch of lawn restored trees that had started dehydrating in Liberia. It has been suggested that small inner branches be pruned from old, ineffective trees to stimulate bearing. In Thailand, the tree is said to take 12 to twenty years to fruit. In Panama and Puerto Rico trees grown from large seed and provided good culture have actually borne in 6 years.
Season and Harvesting
At low altitudes in Ceylon the fruit ripens from May to July; at higher elevations, in July and August or August and September. In India, there are 2 distinct fruiting seasons, one in the monsoon duration (July-October) and another from April through June. Puerto Rican trees in full sun fruit in July and August; shaded trees, in November and December.
Cropping is irregular and the yield varies from tree to tree and from season to season. The very first crop might be 200 to 300 fruits. Typical yield of a full-grown tree has to do with 500 fruits. The yield steadily increases approximately the 30th year of bearing when crops of 1,000 to 2,000 fruits might be obtained. In Madras, private trees between the ages of 20 and 45 years have borne 2,000 to 3,000 fruits. Productivity gradually decreases thereafter, though the tree will still be fruiting at 100 years of age.
Ripeness is assessed by the complete development of color and slight softening. Selecting may be done when the fruits are somewhat underripe however they must be fully mature (developed) or they will not ripen after choosing. The fruits should be collected by hand from ladders or by means of a cutting pole and not be enabled to fall.
In dry, warm, closed storage, mangosteens can be held 20 to 25 days. Longer periods trigger the external skin to strengthen and the rind to become rubbery; later, the rind hardens and ends up being hard to open and the flesh turns dry.
Ripe mangosteens keep well for 3 to 4 weeks in storage at 40º to 55º F (4.44 º-12.78 º C). Trials in India have actually revealed that maximum conditions for cold storage are temperature levels of 39º to 42º F (3.89 º-5.56 º C) and relative humidity of 85 to 90%, which maintain quality for 49 days. It is advised that the fruits be wrapped in tissue paper and jam-packed 25-to-the-box in light wooden cages with excelsior cushioning. Fruits chose somewhat unripe have been delivered from Burma to the UK at 50º to 55º F (10º-12.78 º C). From 1927 to 1929, trial shipments were made from Java to Holland at 37.4 º F (around 2.38 º C) and the fruits kept in good condition for 24 days.
Pests and Diseases
Couple of pests have actually been reported. A leaf-eating caterpillar in India might possibly be the same as that which attacks new shoots in the Philippines and which has actually been recognized as Orgyra sp. Of the tussock moth family, Lymantridae. A small ant, Myrnelachista ramulorum, in Puerto Rico, colonizes the tree, tunnels into the trunk and branches, and damages the brand-new growth. Termites sometimes deface the fruits with little bites and scratches. Completely ripe fruits are attacked by monkeys, bats and rats in Asia.
In Puerto Rico, thread blight triggered by the fungi, Pellicularia koleroga, is typically seen on branchlets, foliage and fruits of trees in shaded, humid areas. The fruits might end up being coated with webbing and messed up. In Malaya, the fungi, Zignoella garcineae, gives rise to “canker”– tuberous growths on the branches, causing a deadly dying-back of foliage, branches and ultimately the whole tree. Breakdown in storage is caused by the fungis Diplodia gossypina, Pestalotia sp., Phomopsis sp., Gloeosporium sp., and Rhizopus nigricans.
A major physiological issue called “gamboge” is evidenced by the exuding of latex onto the outer surface area of the fruits and on the branches during periods of heavy and constant rains. It does not impact eating quality. Fruit-cracking might occur because of extreme absorption of moisture. In broken fruits the flesh will be inflamed and mushy. Bruising brought on by the force of storms may be an essential consider both of these abnormalities. Fruits exposed to strong sun might likewise exhibit latex. Mangosteens produced in Honduras frequently have crystal-like “stones” in the flesh and they may render the fruit completely inedible. 
Nutritional Value Of Mangosteen
- Calories: 63
- Protein: 0.5 g
- Dietary Fiber: 1.8 g
- Carbohydrates: 17.91 g
- Calcium: 10mg
- Protein: 0.41 g
- Iron: 0.36 mg
- Water: 81g
- Fat: 0.4 g
- Vitamin A: 35IU
- Vitamin C: 2.9 mg 
Health Advantages of Mangosteen
It might prevent cancer
Mangosteen plants include few natural compounds. One of those compounds is xanthones. As per studies, xanthones have antioxidant and anti-inflammatory residential or commercial properties that may assist in preventing and treating cancer-causing cells. In addition, depending on their structures, xanthones show a large range of biological functions. They consist of antihypertensive, antioxidative, antithrombotic, and anti-cancer homes.
These compounds avoid the oxidative tension of cells because of antioxidants in them. Oxidative tension describes the imbalance in between oxygen and complimentary radicals in the body. Free radicals are extremely reactive and unsteady particles. Their instability activates the procedure of oxidative tension. It ultimately damages the cells and their essential parts like the cell membrane, DNA, proteins and so on. Oxidative tension results in extreme conditions like cancer, heart problem and diabetes.
In addition to xanthones, mangosteen also consists of Vitamin C and folate. As per research study, these substances are also anti-oxidants and are therefore valuable in handling malignant cells.
Controls Blood Glucose
Insulin is the hormone responsible for managing the sugar level in the body. Insulin resistance happens when cells in various parts of the body like the liver, fat and muscles stop working to take in glucose from the blood. This condition creates an imbalance in blood sugar levels, resulting in diabetes.
Enhances Immune System
A healthy immune system is of fantastic importance for the proper functioning of the body. Subsequently, it protects the body from harmful microorganisms, viruses, germs, and toxic substances launched by them. For that reason, it is important to have a robust immune system to ward off any disease.
Mangosteen is a great source of vitamin C. Vitamin C is typically referred to as ascorbic acid and is water-soluble. As per studies, it aids in preserving a healthy immune system. Nevertheless, considering that our body can not produce vitamin C, we must get it from our day-to-day foods.
Vitamin C is a vital nutrient. It supports numerous cellular functions of our body’s adaptive body immune systems, enhancing the immune system. As an antioxidant, it can assist the body fight complimentary radicals, lowering swelling and increasing resistance. In addition, Vitamin C aids in the recovery of injuries and the repair and upkeep of healthy skin, gums, teeth and bones and cartilage (a difficult tissue covering the bones).
Folate is a kind of Vitamin B. It is a vital component for producing and promoting healthy cells in our bodies. In addition, folate improves the immune system. As per research studies, folate consumption increases the production of T cells that increase the body’s immune reaction.
Maintains Healthy Skin
The anti-inflammatory and antioxidant nature of mangosteen promotes healthy skin. The skin’s renewal process slows down by inflammation. Antioxidants help the skin rejuvenate itself and repair damage by lowering inflammation. Vitamin C, a constituent of mangosteen, assists improve collagen development, vital for vibrant skin.
Great lines, wrinkles, loose skin, acne breakouts, and so on, are all indications of oxidative tension. As a result, they break down collagen, obstructs the skin’s natural repair process, and triggers swelling. Antioxidants can help avoid and fix these signs by neutralising totally free radicals, providing skin a more younger look.
Free radicals and routine sun exposure can trigger changes in the production of skin’s melanin. As a result, the skin establishes dark spots and irregular complexion. Anti-oxidants can assist avoid irregular skin coloring by reducing photodamage. Some anti-oxidants (like vitamin C) also block tyrosinase, an enzyme that promotes the generation of melanin.
Consists Of Antibacterial Characteristic
Mangosteen’s antimicrobial residential or commercial properties hinder the development of a broad variety of bacteria and fungi. For instance, mangosteen contains xanthones that prevent bacterias like E. Coli, Pseudomonas aeruginosa (which causes pneumonia, utis, and other infections in humans).
Xanthones have an unique chemical structure known as the tricyclic aromatic system, linked to antibacterial activity. It is also helpful against both normal and antibiotic-resistant Staphylococcus aureus germs, which causes numerous health problems in humans. Like boils and abscesses on the skin, pneumonia, and joint infections. Mangosteen fruit extracts also prevent the development of Mycobacterium TB (the tuberculosis-causing bacteria).
Prevents Heart Problem
Inflammation increases the development of plaque and blood clots in arteries setting off stroke and heart attacks. Our body takes these plaques as a foreign substance. They should not be in the blood vessel. The body tries to separate the plaque from the streaming blood. Nevertheless, it sometimes so occurs that the plaque ruptures, enabling its walled-off components to contact blood, leading to the formation of a blood clot.
The blockage of arteries in the heart by blood clots causes a cardiac arrest. According to research studies, mangosteen has anti-inflammatory homes. As a result, it limits C reactive protein level that triggers inflammation.
Healthy Mangosteen Dish
1. Thai Style Fruit Salad
- Serving: 1
- Cooking Time: 15 mins
- Hot chilli: 6
- Garlic: 1 Clove
- Lime Juice: 1/2 tbsp
- Fish sauce: 1/2 tablespoon
- Palm sugar: 1/2 tbsp
- Mixed fruits consisting of mangosteen: 2/3 cups
- Nuts: 1/2 cups
- Blanched Prawns: 5
- Slice or shred all the fruits you have, such as mangosteen, carrots, tomatoes, beans, corn and grapes.
- Grind the chilli and garlic in a mortar and pestle. Include as many chillies as you want, depending upon how spicy you want.
- Add lime juice, palm sugar and fish sauce to the crushed chilli and garlic. Then blend it.
- Include this mix to the sliced fruits in addition to the blanched prawn. Serve with nuts as toppings.
2. Mangosteen Chia Shake Bowl
- Servings: 1
- Cooking time: 5 minutes.
- Chia seeds (soaked in water for an hour); 1 tbsp
- Mangosteens: 2
- Half mango
- Mixed seeds: 1 tbsp
- Milk: 1 cup
- Ice cubes
- Mix drenched chia seeds, mangosteen, mango, combined seeds, milk and a few ice cubes in a blender till it ends up being smooth and thick.
- Include some jaggery to the puree if you wish to.
- Put the healthy smoothie in a bowl and garnish it with fruits and nuts. 
Mangosteen: 7 Unanticipated Side Effects Of The Tropical Fruit
May Slow Down Blood Clot
Mangosteen has actually been discovered to slow down blood clot. It can increase the risk of bleeding in vulnerable individuals. This is particularly true when the fruit is taken along with certain drugs that increase the risk.
Consuming mangosteen may likewise increase the threat of bleeding during or after surgical treatment. Prevent taking it at least two weeks before a set up surgery.
May Cause Lactic Acidosis
Lactic acidosis is a medical condition characterized by the accumulation of lactate within the body. This takes place due to the formation of excessively low ph in the blood stream. This suggests the build-up of excess acid within the body’s system.
A study highlights severe lactic acidosis that happens due to the use of mangosteen juice as a dietary supplement. Based on anecdotal reports, the symptoms associated with this condition may include weakness and queasiness. If left untreated, this condition can result in an acid build-up in the body to dangerous levels– leading to shock and death.
May Disrupt Chemotherapy
Animal studies have shown the anticancer results of mangosteen. However studies on people are yet to be performed. Mangosteen items are often marketed to cancer patients as dietary supplements.
Some research study shows that these supplements might disrupt cancer treatment and negatively impact blood sugar levels. In another report, particular antioxidant supplements were found to minimize the efficiency of conventional radiation treatments.
As mangosteen supplements are frequently marketed for their antioxidant capacity, it is necessary to exercise caution.
May Cause Gastrointestinal Issues
Some research study has revealed topics experiencing intestinal signs after consuming mangosteen for over 26 weeks. Some of these symptoms included bloating, diarrhea, gastric reflux, and constipation.
May Cause Sedation
The derivatives of mangosteen triggered anxiety and sedation in rats. The impacts had actually also resulted in decreased motor activity. However, more research studies in people are needed to establish these impacts.
May Cause Allergies
There is limited evidence if mangosteen can cause allergic reactions. But anecdotal evidence suggests that it might trigger reactions in individuals sensitive to the fruit. If you experience any reaction after consuming mangosteen, stop consumption and visit your doctor.
May Cause Complications During Pregnancy
The safety of mangosteen during pregnancy or breastfeeding is not yet established. Thus, stay safe and prevent use. You might consult your doctor relating to the very same.
Most of the negative results of mangosteen are yet to be developed by concrete research study. If you are generally susceptible to allergic reactions or responses, you might want to speak with your physician before taking the fruit.
Why Is Mangosteen Banned?
Mangosteen was prohibited in the United States by the FDA since it could be a host to import Asian fruit flies into the nation. The restriction was lifted owing to preventive irradiation of the fruit, which was a treatment done to decontaminate it. The technique of irradiation is still under debate regardless of its claims that it does not compromise with the taste and nutrition of the fruit.
However, food supplements containing mangosteen continue to be prohibited by the US FDA. Such supplements are primarily unregistered, and very little is known if they may cause any adverse effects. 
Medications that slow blood clotting (Anticoagulant/ Antiplatelet drugs) Interaction Score: Moderate Be cautious with this combination.Talk with your health company.
Mangosteen may slow blood clot and increase bleeding time. Taking mangosteen along with medications that also sluggish clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clot consist of aspirin, clopidogrel (Plavix), dalteparin (Fragmin), dipyridamole (Persantine), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others. 
Unique Precautions and Warnings
When taken by mouth: Mangosteen is potentially safe when considered up to 12 weeks. It may trigger irregularity, bloating, nausea, throwing up, and exhaustion.
When applied to the gums: Mangosteen gel is possibly safe.
Pregnancy and breast-feeding: There isn’t adequate trustworthy details to understand if mangosteen is safe to utilize when pregnant or breast-feeding. Remain on the safe side and avoid usage.
Bleeding disorders: Mangosteen might slow blood clotting. Taking mangosteen might increase the threat of bleeding in people with bleeding conditions.
Surgical treatment: Mangosteen may slow blood clot. Taking mangosteen may increase the threat of bleeding throughout or after surgical treatment. Stop taking mangosteen 2 weeks prior to surgical treatment. 
Mangosteen triggers allergic reactions in some individuals and for this reason it is advised for you to avoid this fruit, in case you are prone to hypersensitivity. 
The bottom line
Mangosteen is a small purple fruit that grows in Southeast Asia. It is difficult to grow and import into the U.S.
Research studies have actually suggested that the fruit has antioxidant and anti-inflammatory properties. Nevertheless, there is not yet sufficient evidence to conclusively show this.
Some medications include mangosteen as a component. These include drugs for obesity and gum disease. People who are pregnant, nursing, have a blood condition, or are about to have an operation must avoid mangosteen-based medications.