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Fontainea picrosperma, commonly referred to as the blushwood tree, is a jungle tree in the family Euphorbiaceae endemic to Queensland in Australia, where it grows on the Atherton Tablelands. [1]
Summary
An anti-cancer drug called EBC-46 has actually been developed from an extract of the fruits of Fontainea picrosperma. Trials have shown that it has activity against 4 different types of tumours, consisting of basal-cell carcinoma, cancer malignancy, squamous cell carcinoma and breast adenocarcinoma. The fruits are harmful to people if consumed. [3]
Stem
Copious watery red exudate appearing quickly in the blaze.
Leaves
Oil dots visible with a lens, practically noticeable to the naked eye. Leaf blades about 7-15 x 2-5 cm. Petioles shallowly carried or flattened on the upper surface area, the margins angular or a little winged. Young shoots dressed in pale yellowish hairs. Branch exudate like that in the blaze.
Flowers
Petals in male flowers about 5-6 mm long and about 7-8 mm long in female flowers. Petals largely white, tomentose. Disk orange. Preconceptions ten, radiating like octopus arms.
Fruit
Fruit about 25 mm long and about 20 mm diam. Endocarp rather thick, stellate in transverse area, frequently 5-pointed in transverse section.
Seedlings
Cotyledons broadly ovate, about 45-55 x 30-40 mm, 3-veined at the base. At the tenth leaf stage: leaves lanceolate to ovate, peak acuminate, base obtuse, upper surface area of leaf blade glabrous; oil dots little, indistinct, noticeable only with a lens. Seed germination time 26 to 58 days.
Circulation and Ecology
Endemic to NEQ, limited to the Atherton Tableland. Altitudinal range from 700-1100 m. Grows as an understory tree in well industrialized rain forest.
Natural History and Notes
Fallen fruit eaten by Cassowaries and Musky Rat-kangaroos. [4]
This trees grow just and solely In the far north-eastern part of Queensland Australia, in the rainforests grows the Blushwood Berry tree referred to as Hylandia Dockrillii.
It grows at high elevations of 400 to 1100 meters in the well-developed rainforest at different areas and reaches heights of approximately 25 meters. Blushwood berries are the fruit of the Blushwood tree. The tree’s berries have has extraordinary medical residential or commercial properties and its primary element EBC-46 might take top priority in repairing the immune system and DNA harmed cells in the near future of holistic treatments.
Blushwood Berry
Chemical extracts from the berries of Australian blushwood tree (Hylandia dockrillii) have actually revealed to be reliable in treating cancers such as cancer malignancy and breast cancer. Blushwood berry trees are stated to be specifically seen in the rainforests of Far North Queensland, Australia. Nevertheless, attempts to grow them in a greenhouse environment are being done.
EBC-46 Extract
Researchers have developed a drug called EBC-46 from the substance extracts of blushwood berries which are said to have anticancer residential or commercial properties. Researchers state that the preparation of the drug is a complicated strategy and human trials are presently being carried out. The anticancer impacts of this berry were first reported in 2004.
What does it do?
It is thought that the drug acts straight, denies the cancer cells off their oxygen supply, and likewise triggers the host immune response. Cancer cells exposed shriveling, shrinking, and cell death microscopically quickly after exposure to the drug.
EBC-46 triggers an enzyme called protein kinase C; however, mechanism included is still uncertain. Nearly 75% of preclinical trials exposed appealing results with very little relapse in 1-year follow-up period and no side effects. The drug was checked in quickly available growths; however, its function in metastatic growths is yet to be ascertained. Phase 1 scientific human trials in cutaneous strong tumors such as melanoma squamous cell cancer (SCC), head and neck SCC, basal cell cancer, and Merkel cell cancer are underway. EBC-46 is a trademarked chemotherapeutic drug.
The seeds then goes through an extracting process, The EBC-46 element is drawn out from seeds compounds, made into liquid, strong pills or powder. Finally it gets packaged in the UK’s finest business. [5]
How Blushwood Berries Can Ruin Cancer Cells Almost Instantly
A research study performed at QIMR Berghofer Medical Research Institute in Queensland, Australia has recently shed new light on what might end up being the next huge cancer treatment: the blushwood berry (Hylandia dockrillii). This naturally taking place fruit includes compounds that began killing off cancer cells almost instantly when studied in the laboratory.
Chemotherapy and radiation are poisonous and included harsh negative effects, often making the ill feel a lot more ill. The current research on this fantastic berry might indicate new, natural treatments for cancer on the horizon.
Blushwood Berries– Where they Originate from
Blushwood berries are the fruit of the blushwood tree, which is known to grow in only one area of the world: the rain forests of Far North Queensland, Australia.
These tropical trees are not found anywhere else on the globe, however grow in abundance near Australia’s northeastern suggestion.
These particular trees need very niche conditions to prosper– conditions which can only be found in specific portions of Far North Queensland, Australia.
Considering their usefulness as shown by the latest cancer research study released in PLOS One, some are wondering if they could be grown in a greenhouse environment, so that individuals all over the world might benefit from their cancer-killing properties.
Blushwood Berries– What kind of Cancer they Get rid of
The researchers at QIMR Berghofer Medical Research Institute, headed by Dr. Glen Boyle, used a speculative drug produced from the seeds of blushwood berries called EBC-46. They used this drug to deal with spots of cancer malignancy (the most lethal type of skin cancer) on pets, cats and horses.
The topics were identified by vets and offered a poor prognosis, many being thought about prospects for euthanasia prior to participating in the research study.
Surprisingly, these animals that had been on death’s door prior to the research study had their cancer malignancy growths vanish after treatment in the lab by Dr. Boyle and his group of researchers.
Growths were Gone within 48 Hours
When the EBC-46 was injected into the cancerous cells on the subjects, the growths reacted by turning a dark color, then falling off.
The derivative from the blushwood berry is believed to cut off oxygen supply to the cancer cells, enabling the elimination of growths without the need for surgical treatment, chemotherapy or radiation therapy.
The scientists reported that most of the topics’ growths– formerly thought about a lost bring on by veterinarians– were gone within 48 hours of being injected with EBC-46.
Under the microscope, the individual cancer cells started shriveling up and dying within simple momentsof entering into contact with the EBC-46.
What the Future of Cancer Treatment Could Be?
The discovery of the efficiency of EBC-46 is interesting news on the planet of cancer treatment.
D.r Boyle states the findings of the pre-clinical trials at QIMR Berghofer suggest the drug could be effective in human patients.
” In most cases the single injection treatment caused the loss of viability of cancer cells within four hours, and eventually damaged the tumors.”.
Dr. Boyle states EBC-46 operate in part by setting off a cellular reaction which successfully cuts off the blood supply to the tumor. “In more than 70 percent of pre-clinical cases, the response and remedy was long-lasting and long-lasting, with extremely little regression over a duration of 12 months.”.
” We should stress at this moment that EBC-46 will just be trialed in the short-term for tumors which can be accessed by direct injection or topical application,” Dr Boyle said.
” There is no proof to recommend EBC-46 would work against metastatic cancers.”.
Further studies utilizing human participants could serve to show the blushwood berry to be nature’s surprise cancer cure. [6]
Human trials for possible cancer treatment uncovered in Australian jungle underway
Australian scientists are trialling the cancer-fighting homes in fruit from rainforest trees in Far North Queensland.
EBC-46 is a particle found in the berries of the rainforest tree blushwood (fontainea picrosperma), which grows on the Atherton Tablelands.
” It’s a small particle which deals with the body to destroy cancer, rather than being a chemo-therapy method which can act against the body,” Dr Victoria Gordon, CEO of Q-Biotics, informed TODAY.
She discussed the innovative treatment worked by injecting the molecule into the tumour website.
” We get complete tumour destruction in 5 to seven days, great recovery … and no considerable negative effects”.
The impacts EBC-46 has actually been trialled with animals, including Dr Gordon’s 18-year-old family pet dog who had an oral cancer malignancy.
” We injected the drug (EBC-46) and it simply appeared to liquefy (the tumour),” she stated.
Early stages of human trials are underway, with 14 clients treated up until now.
” We have actually had no significant negative effects and great results in six tumour types”.
Dr Gordon stressed there is still a “a long, difficult roadway ahead” before a pharmaceutical can be developed from the drug. [7]
Appealing ‘cancer-cure’ berries taken off sale for fear of hazardous home remedy poisoning
‘ In most cases the single injection treatment caused the loss of practicality of cancer cells within four hours, and eventually ruined the tumours,’ lead scientist Dr Glen Boyle told the ABC.
Sellers of the native tree are rushing to take the rainforest range off sale however, after fears that individuals could be poisoned attempting to create homemade cancer treatments.
‘ Our issue was people were simply going to grow it, get some fruit, crush it up and consume it,’ Roger Smith, supervisor of Yuruga Native Plant Nursery informed the Cairns Post.
Scientist Steven Ogbourne of the University of Sunshine Coast says it’s not that simple, and a complex treatment is needed to extract the cancer-fighting compound.
Human trials are currently being prepared for the appealing drug. [8]
Conclusion
Fontainea picrosperma (Blushwood) are uncommon small shy spindly dioecious, damp enclosed jungle understorey trees requiring canopy security. Some Fontaineas types survive in hasher conditions than the Blushwood. F.venosa can grow to 60 feet compared to 15 feet for Blushwood that grows at 2,300 ft to 3,600 ft. Blushwoods hate a cool temperature level and need the nutrients, moisture and the security of a wet rain forest. Alkaloids discovered in all Fontainea sap causes cancerous tumours to ablate, but there are only 200 of these native trees in the world, so you will not legally be able to import these plants into the U.S.A. out of Australia. [9]
References
- https://en.wikipedia.org/wiki/Fontainea_picrosperma
- https://apps.des.qld.gov.au/species-search/details/?id=17128
- https://www.herbal-organic.com/en/herb/197290
- https://apps.lucidcentral.org/rainforest/text/entities/fontainea_picrosperma.htm
- https://www.blushwoodforest.co.uk/
- https://www.seychellesweekly.com/2016/February%2015,%202016/beaute-sante1_blushwood_berries.html
- https://www.9news.com.au/health/cancer-fighting-berry-discovered/781a0d81-28f2-4f61-ba56-7895bc3e51ce
- https://www.thatslife.com.au/fears-of-cancer-cure-home-remedy-poisoning
- https://www.daleysfruit.com.au/forum/blushwood2/